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X-WR-CALNAME:René Salazar Speaker Series in Collaboration with Out@Broad
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260714T074152Z
UID:tag:localist.com\,2008:EventInstance_49524245988474
DTSTART:20250610T180000Z
DTEND:20250610T190000Z
DESCRIPTION:Join us for a talk by Dr. Julian Avila-Pacheco\, Associate Dire
 ctor of Metabolite Profiling at the Broad Institute of MIT and Harvard\, a
 s he shares groundbreaking findings on a newly identified brain metabolite
  with potential implications for treating tuberculous meningitis (TBM)\, t
 he deadliest form of tuberculosis. Through a comprehensive metabolomic ana
 lysis of cerebrospinal fluid from TBM patients\, Dr. Avila-Pacheco and col
 leagues discovered and characterized gamma aminobutyric acid-arginine (GAB
 A-Arg)\, a dipeptide linked to survival outcomes. Detected primarily in br
 ain regions such as the hypothalamus and hippocampus\, GABA-Arg appears to
  play a role in stress-response pathways and may offer a protective effect
 . This talk will highlight how GABA-Arg was identified\, its correlation w
 ith oxidative stress\, and its promise as a target for host-directed thera
 pies in TBM. Don’t miss this opportunity to explore the intersection of 
 neuroscience\, infectious disease\, and metabolomics!
LOCATION:
SUMMARY:René Salazar Speaker Series in Collaboration with Out@Broad
URL;VALUE=URI:https://events.broadinstitute.org/event/rene-salazar-speaker-
 series-in-collaboration-with-outbroad
CATEGORIES:Talks
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