Join us on Wednesday, May 7 for our an MIA Community Day! Form new connections, inform the next MIA calendar, and enjoy some amazing breakfast. 

 

📅 May 7

💬 Community Day

❓ Fill out the MIA questionnaire to share your feedback

 

Hosted by the Eric and Wendy Schmidt Center, the MIA Initiative (Models, Inference & Algorithms) supports learning and collaboration across the interface of biology and medicine with mathematics, statistics, machine learning, and computer science. We bring together scientists on Wednesdays in Acadia (Broad Institute – 75 Ames St., M1) and virtually. A primer with breakfast starts at 9:00 am, followed by a seminar and discussion at 10:00 am and 10:50 am, respectively.

 

💌 Join our mailing list: bit.ly/MIACast 

🧑‍🏫 Read the abstracts: broad.io/MIA 

📺 Watch previous talks: broad.io/MIAPlaylist

❓ Ask questions: mia-team@broadinstitute.org 

 

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🌸 Spring 2025 Schedule 🌸

 

📅 February 12

💬 Aleksandra Walczak

🏫 CNRS European Nuclear Society (ENS)

💡 Immune repertoires: specificity and dynamics

📺 Watch recorded talk

 

💬 Andrea Mazzolini

🏫 Laboratoire de Physique de l'École Normale Supérieure (LPENS)

💡 Extracting dynamical properties of the immune repertoire from noisy sequencing data

📺 Watch recorded talk

 

📅 February 26

💬 Rob Patro

🏫 University of Maryland

💡 Counting is not easy: Assessing and quantifying uncertainty in abundance inferences from high-throughput sequencing data

📺 Watch recorded talk

 

💬 Noor Pratap Singh

🏫 University of Maryland

💡 Uncertainty-aware analysis of RNA-Seq data using a tree-based framework

📺 Watch recorded talk

 

📅 March 5 - Flash talks 

📺 Watch recorded talks

 

9:00 am

 

💬 Isabella Boyle

🏫 Cancer Data Science, Broad Institute

💡 GeneTEA: gene-term enrichment with natural language processing

 

💬 Francesca Rissom

🏫 Iqbal Lab | Ladders 2 Cures Accelerator, Broad Institute

💡 Comparing protein language models through embedding space comparison

 

💬 Viki Schuster

🏫 Eric and Wendy Schmidt Center, Broad Institute

💡 Interpreting gene expression models with sparse autoencoders

 

10:00 am

 

💬 Phillip Nicol

🏫 Irizarry Lab, Harvard School of Public Health

💡 Identifying spatially variable genes by projecting to morphologically relevant coordinates

 

💬 Uthsav Chitra

🏫 Eric and Wendy Schmidt Center, Broad Institute

💡 Mapping the topography of spatial gene expression with interpretable deep learning

 

💬 Baris Ekim

🏫 Berger Lab, MIT and Popic Lab, Broad Institute

💡 Minimizer-space computation in genomics

 

📅 March 12

💬 Rishwanth Raghu

🏫 Princeton University

💡 Heterogeneous reconstruction in cryo-EM

 

💬 Ellen Zhong

🏫 Princeton University

💡 Machine learning for visualizing structural landscapes inside the cell

 

📅 March 19

💬 Andrew White

🏫 FutureHouse, University of Rochester
💡 A progress report on the automation of science

💬 Sam Cox
🏫 FutureHouse, University of Rochester
💡 Automating chemistry with LLM-based agents

 

📅 April 2

💬 Gokcen Eraslan

🏫 ReLU, BRAID, Genentech

💡 A primer on DNA foundation modeling

 

💬 Surag Nair

🏫 ReLU, BRAID, Genentech

💡 Nona, a novel multimodal masked modeling framework for functional genomics

 

📅 April 9

💬 Alexandru Dumitrescu, Dani Korpela

🏫 Aalto University

💡 Diffusion for molecule generation

📺 Watch recorded talk

 

💬 Harri Lähdesmäki

🏫 Aalto University

💡 Structured variational autoencoders for prediction and optimization

📺 Watch recorded talk

 

 

📅 May 7

💬 Community Day

❓ Fill out the MIA questionnaire to share your feedback

 

📅 May 14

💬 Jaron Thompson

🏫 University of Wisconsin-Madison, Venturelli Lab

💡 Variational inference for uncertainty quantification of microbial community dynamics

 

💬 Ophelia Venturelli

🏫 University of Wisconsin-Madison, Duke University

💡 TBD

 

📅 May 21

💬 Valentin De Bortoli

🏫 Google DeepMind

💡 Diffusion models, Schrodinger bridges and applications in bio

 

📅 May 28

💬 Faisal Mahmood

🏫 Harvard Division of Medical Sciences

💡 Multimodal, Generative, and Agentic AI for Pathology

 

**If you do not have a Broad badge, please arrive at the 75 Ames St. entrance 10 minutes early with an ID to check in with security. We will escort folks up at 8:55 am and 9:55 am; please email mia-team@broadinstitute.org if you arrive outside of these times.