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Models, Inference & Algorithms (MIA) Meeting

Wednesday, May 28, 2025 9am to 12pm

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Join us on Wednesday, May 28Β for our MIA meeting featuring Faisal Mahmood (Harvard Division of Medical Sciences)!

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πŸ“… May 28

πŸ’¬ Faisal Mahmood

🏫 Harvard Division of Medical Sciences

πŸ’‘ Multimodal, Generative, and Agentic AI for Pathology

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Hosted by the Eric and Wendy Schmidt Center, the MIA Initiative (Models, Inference & Algorithms) supports learning and collaboration across the interface of biology and medicine with mathematics, statistics, machine learning, and computer science. We bring together scientists onΒ Wednesdays in Acadia (Broad Institute – 75 Ames St., M1) and virtually. A primer with breakfast starts at 9:00 am, followed by a seminar and discussion at 10:00 am and 10:50 am, respectively.

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πŸ’Œ Join our mailing list: bit.ly/MIACastΒ 

πŸ§‘β€πŸ« Read the abstracts: broad.io/MIAΒ 

πŸ“Ί Watch previous talks: broad.io/MIAPlaylist

❓ Ask questions: mia-team@broadinstitute.orgΒ 

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***

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🌸 Spring 2025 Schedule 🌸

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πŸ“… February 12

πŸ’¬ Aleksandra Walczak

🏫 CNRS European Nuclear Society (ENS)

πŸ’‘ Immune repertoires: specificity and dynamics

πŸ“Ί Watch recorded talk

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πŸ’¬ Andrea Mazzolini

🏫 Laboratoire de Physique de l'Γ‰cole Normale SupΓ©rieure (LPENS)

πŸ’‘ Extracting dynamical properties of the immune repertoire from noisy sequencing data

πŸ“Ί Watch recorded talk

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πŸ“… February 26

πŸ’¬ Rob Patro

🏫 University of Maryland

πŸ’‘ Counting is not easy: Assessing and quantifying uncertainty in abundance inferences from high-throughput sequencing data

πŸ“Ί Watch recorded talk

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πŸ’¬ Noor Pratap Singh

🏫 University of Maryland

πŸ’‘ Uncertainty-aware analysis of RNA-Seq data using a tree-based framework

πŸ“Ί Watch recorded talk

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πŸ“… March 5 - Flash talksΒ 

πŸ“Ί Watch recorded talks

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9:00 am

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πŸ’¬ Isabella Boyle

🏫 Cancer Data Science, Broad Institute

πŸ’‘ GeneTEA: gene-term enrichment with natural language processing

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πŸ’¬ Francesca Rissom

🏫 Iqbal Lab | Ladders 2 Cures Accelerator, Broad Institute

πŸ’‘ Comparing protein language models through embedding space comparison

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πŸ’¬ Viki Schuster

🏫 Eric and Wendy Schmidt Center, Broad Institute

πŸ’‘ Interpreting gene expression models with sparse autoencoders

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10:00 am

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πŸ’¬ Phillip Nicol

🏫 Irizarry Lab, Harvard School of Public Health

πŸ’‘ Identifying spatially variable genes by projecting to morphologically relevant coordinates

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πŸ’¬ Uthsav Chitra

🏫 Eric and Wendy Schmidt Center, Broad Institute

πŸ’‘ Mapping the topography of spatial gene expression with interpretable deep learning

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πŸ’¬ Baris Ekim

🏫 Berger Lab, MIT and Popic Lab, Broad Institute

πŸ’‘ Minimizer-space computation in genomics

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πŸ“… March 12

πŸ’¬Β Rishwanth Raghu

🏫 Princeton University

πŸ’‘ Heterogeneous reconstruction in cryo-EM

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πŸ’¬ Ellen Zhong

🏫 Princeton University

πŸ’‘ Machine learning for visualizing structural landscapes inside the cell

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πŸ“… March 19

πŸ’¬ Andrew White

🏫 FutureHouse, University of Rochester
πŸ’‘ A progress report on the automation of science


πŸ’¬ Sam Cox
🏫 FutureHouse, University of Rochester
πŸ’‘ Automating chemistry with LLM-based agents

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πŸ“… April 2

πŸ’¬ Gokcen Eraslan

🏫 ReLU, BRAID, Genentech

πŸ’‘ A primer on DNA foundation modeling

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πŸ’¬ Surag Nair

🏫 ReLU, BRAID, Genentech

πŸ’‘ Nona, a novel multimodal masked modeling framework for functional genomics

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πŸ“… April 9

πŸ’¬ Alexandru Dumitrescu, Dani Korpela

🏫 Aalto University

πŸ’‘ Diffusion for molecule generation

πŸ“Ί Watch recorded talk

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πŸ’¬ Harri LΓ€hdesmΓ€ki

🏫 Aalto University

πŸ’‘ Structured variational autoencoders for prediction and optimization

πŸ“Ί Watch recorded talk

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πŸ“… May 7

πŸ’¬ Community Day

❓ Fill out the MIA questionnaire to share your feedback

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πŸ“… May 14

πŸ’¬ Jaron Thompson

🏫 University of Wisconsin-Madison, Venturelli Lab

πŸ’‘ Variational inference for uncertainty quantification of microbial community dynamics

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πŸ’¬ Ophelia Venturelli

🏫 University of Wisconsin-Madison, Duke University

πŸ’‘ TBD

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πŸ“… May 21

πŸ’¬ Valentin De Bortoli

🏫 Google DeepMind

πŸ’‘ Diffusion models, Schrodinger bridges and applications in bio

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πŸ“… May 28

πŸ’¬ Faisal Mahmood

🏫 Harvard Division of Medical Sciences

πŸ’‘ Multimodal, Generative, and Agentic AI for Pathology

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**If you do not have a Broad badge, please arrive at the 75 Ames St. entrance 10 minutes early with an ID to check in with security. We will escort folks up at 8:55 am and 9:55 am; please email mia-team@broadinstitute.org if you arrive outside of these times.